STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Noca_4350Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.992
Noca_3184
Fructose PTS system EIIBC or EIIC component; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit; KEGG: mmc:Mmcs_0080 phosphotransferase system, fructose IIC component; TC 4.A.2.1.4; TC 4.A.2.1.4; TC 4.A.2.1.4.
  
 
 0.991
Noca_2530
KEGG: cdi:DIP1310 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.988
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.977
Noca_2541
TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region; KEGG: rha:RHA1_ro07186 transketolase; Belongs to the transketolase family.
  
 
 0.972
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
 
 0.972
Noca_1175
PFAM: Transaldolase; KEGG: pac:PPA0454 transaldolase.
  
 
 0.961
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.961
Noca_2539
PFAM: phosphoglucose isomerase (PGI); KEGG: lxx:Lxx11600 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.960
Noca_1066
TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sma:SAV3215 putative glycerol-inducible protein.
  
 
 0.952
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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