STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_4453PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: gbe:GbCGDNIH1_1185 dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (427 aa)    
Predicted Functional Partners:
Noca_4454
PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: bme:BMEII0061 2-oxoisovalerate dehydrogenase alpha and beta subunit.
 
 0.999
Noca_4508
PFAM: Transketolase, central region; Transketolase domain protein; KEGG: sco:SCO3816 putative branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 0.995
Noca_4509
PFAM: dehydrogenase, E1 component; KEGG: tfu:Tfu_0180 pyruvate dehydrogenase (lipoamide).
 
 0.995
Noca_3518
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: pac:PPA1227 dihydrolipoamide dehydrogenase.
 0.991
Noca_2304
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: tfu:Tfu_0994 dihydrolipoamide dehydrogenase.
 0.989
Noca_1993
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.967
Noca_2105
2-oxo-acid dehydrogenase E1 component homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.967
Noca_3770
PFAM: Transketolase, central region; Transketolase domain protein; KEGG: tte:TTE0689 Thiamine pyrophosphate-dependent dehydrogenases, E1 component beta subunit.
 
 0.963
Noca_0888
KEGG: rxy:Rxyl_1676 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 0.960
Noca_3769
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component; KEGG: tte:TTE0688 Thiamine pyrophosphate-dependent dehydrogenases, E1 component alpha subunit.
 
 0.959
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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