Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Noca_4615KEGG: sco:SCO4674 hypothetical protein. (127 aa)    
Predicted Functional Partners:
Noca_4618
PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1; KEGG: rha:RHA1_ro04995 probable multidrug resistance transporter, MFS superfamily.
 
   
 0.811
Noca_4616
KEGG: mmc:Mmcs_1143 hypothetical protein.
  
    0.776
Noca_4617
Cellulase; PFAM: glycoside hydrolase, family 6; KEGG: mtu:Rv0062 cellulase / endoglucanase; Belongs to the glycosyl hydrolase family 6.
       0.773
Noca_1196
PFAM: protein of unknown function DUF664; KEGG: sma:SAV7047 hypothetical protein.
 
   
 0.682
Noca_2107
PFAM: protein of unknown function DUF664; KEGG: sco:SCO2990 hypothetical protein.
 
   
 0.616
Noca_4667
KEGG: sco:SCO4220 hypothetical protein.
 
  
 0.551
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.539
Noca_4614
RNA polymerase, sigma subunit, ECF family; PFAM: sigma-70 region 2 domain protein; Tetratricopeptide TPR_2 repeat protein; Sigma-70, region 4 type 2; KEGG: sma:SAV1195 putative RNA polymerase ECF-subfamily sigma factor.
       0.498
Noca_4613
PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: ade:Adeh_0397 thimet oligopeptidase.
 
    0.497
Noca_2836
KEGG: sco:SCO2460 hypothetical protein.
 
  
 0.481
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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