STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_4646PFAM: protein of unknown function DUF488; KEGG: nha:Nham_3631 protein of unknown function DUF488. (111 aa)    
Predicted Functional Partners:
Noca_0935
PFAM: Uracil-DNA glycosylase superfamily; KEGG: fal:FRAAL6229 uracil-DNA glycosylase.
      0.682
Noca_4645
PFAM: Patatin; KEGG: rha:RHA1_ro01898 possible lipid acyl hydrolase.
       0.598
Noca_4647
PFAM: NC domain protein; KEGG: syf:Synpcc7942_2528 hypothetical protein.
       0.588
Noca_4644
Hypothetical protein.
       0.579
Noca_4642
Hypothetical protein.
       0.578
Noca_4643
PFAM: Sigma-70, region 4 type 2; KEGG: rpa:RPA1819 RNA polymerase ECF-type sigma factor, possible FecI.
       0.576
Noca_4648
PFAM: GtrA family protein; KEGG: tfu:Tfu_2548 hypothetical protein.
       0.523
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
    0.452
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
       0.432
Noca_4640
KEGG: btk:BT9727_2577 hypothetical protein.
       0.426
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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