STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAC18174.1Conserved hypothetical protein; CE1364, similar to AL138662-26|CAB71831.1| percent identity: 29 in 278 aa. (591 aa)    
Predicted Functional Partners:
gene:10741772
Uncharacterized protein.
 
     0.773
BAC18072.1
Putative sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.645
gene:10741774
Acetolactate synthase.
  
    0.638
BAC18176.1
Putative acetolactate synthase small subunit; CE1366, similar to L09232-3|AAA62430.1| percent identity: 94 in 172 aa.
       0.585
ilvD1
Putative dihydroxy-acid dehydratase; CE1362, similar to AX136925-1|CAC39870.1| percent identity: 90 in 613 aa; Belongs to the IlvD/Edd family.
       0.565
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
    0.539
mscL
Putative large-conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.452
BAC17417.1
Conserved hypothetical protein; CE0607, similar to AL583918-63|CAC29894.1| percent identity: 41 in 113 aa.
  
   
 0.426
gene:10742500
Putative integral membrane protein.
 
     0.419
Your Current Organism:
Corynebacterium efficiens
NCBI taxonomy Id: 196164
Other names: C. efficiens YS-314, Corynebacterium efficiens DSM 44549, Corynebacterium efficiens JCM 11189, Corynebacterium efficiens YS-314, Corynebacterium efficiens str. YS-314, Corynebacterium efficiens strain YS-314
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