node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAC17550.1 | bioA | gene:10741142 | gene:10741835 | CE0740, similar to AL512667-19|CAC21623.1| percent identity: 40 in 274 aa. | Adenosylmethionine--8-amino-7-oxononanoate transaminase; CE1421, similar to AE007027-12|AAK45886.1| percent identity: 59 in 380 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.614 |
BAC17550.1 | bioB | gene:10741142 | gene:10740479 | CE0740, similar to AL512667-19|CAC21623.1| percent identity: 40 in 274 aa. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.966 |
BAC17550.1 | nadE | gene:10741142 | gene:10742866 | CE0740, similar to AL512667-19|CAC21623.1| percent identity: 40 in 274 aa. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.547 |
BAC17603.1 | cobB2 | gene:10741195 | gene:10741055 | Putative NADH pyrophosphatase; CE0793, similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa. | Putative cobalamin biosynthesis protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.908 |
BAC17603.1 | gene:10742850 | gene:10741195 | gene:10742850 | Putative NADH pyrophosphatase; CE0793, similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.915 |
BAC17603.1 | nadD | gene:10741195 | gene:10742688 | Putative NADH pyrophosphatase; CE0793, similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.905 |
BAC17603.1 | nadE | gene:10741195 | gene:10742866 | Putative NADH pyrophosphatase; CE0793, similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.905 |
BAC17603.1 | nadK | gene:10741195 | gene:10741965 | Putative NADH pyrophosphatase; CE0793, similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.901 |
bioA | BAC17550.1 | gene:10741835 | gene:10741142 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; CE1421, similar to AE007027-12|AAK45886.1| percent identity: 59 in 380 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | CE0740, similar to AL512667-19|CAC21623.1| percent identity: 40 in 274 aa. | 0.614 |
bioA | bioB | gene:10741835 | gene:10740479 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; CE1421, similar to AE007027-12|AAK45886.1| percent identity: 59 in 380 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.994 |
bioA | nadE | gene:10741835 | gene:10742866 | Adenosylmethionine--8-amino-7-oxononanoate transaminase; CE1421, similar to AE007027-12|AAK45886.1| percent identity: 59 in 380 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.615 |
bioB | BAC17550.1 | gene:10740479 | gene:10741142 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | CE0740, similar to AL512667-19|CAC21623.1| percent identity: 40 in 274 aa. | 0.966 |
bioB | bioA | gene:10740479 | gene:10741835 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Adenosylmethionine--8-amino-7-oxononanoate transaminase; CE1421, similar to AE007027-12|AAK45886.1| percent identity: 59 in 380 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.994 |
bioB | nadE | gene:10740479 | gene:10742866 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.572 |
cobB2 | BAC17603.1 | gene:10741055 | gene:10741195 | Putative cobalamin biosynthesis protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | Putative NADH pyrophosphatase; CE0793, similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa. | 0.908 |
cobB2 | nadD | gene:10741055 | gene:10742688 | Putative cobalamin biosynthesis protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.931 |
cobB2 | nadE | gene:10741055 | gene:10742866 | Putative cobalamin biosynthesis protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.909 |
cobB2 | nadK | gene:10741055 | gene:10741965 | Putative cobalamin biosynthesis protein; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.908 |
gene:10742850 | BAC17603.1 | gene:10742850 | gene:10741195 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Putative NADH pyrophosphatase; CE0793, similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa. | 0.915 |
gene:10742850 | nadD | gene:10742850 | gene:10742688 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.966 |