STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUN48856.14-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.991
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 0.928
KUN40627.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.921
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
  
 0.914
KUN44701.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.896
KUN48648.1
Protein meaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.873
KUN46673.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.869
rutR_1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.829
KUN44860.1
DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.824
KUN44700.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.822
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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