Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KUN48868.16-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)    
Predicted Functional Partners:
queE
Radical SAM protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.965
KUN48867.1
Trans-aconitate methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.946
KUN49068.1
Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.946
KUN48869.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.940
KUN49067.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.920
queC
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.881
folE
GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.866
folE2
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.866
KUN42315.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.772
KUN47955.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.653
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.