Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN48528.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.924
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 0.921
KUN48205.1
Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.860
KUN41526.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.713
KUN46643.1
Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.699
KUN43664.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.675
KUN45892.1
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.632
hemB
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
  
 
 0.594
KUN47919.1
Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.589
KUN48529.1
Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.566
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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