Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN48284.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)    
Predicted Functional Partners:
hrpB
ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.862
KUN40627.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.775
KUN47679.1
Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
     
 0.699
rpsA
30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.665
KUN47558.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.665
ppsD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.664
KUN40628.1
6-deoxyerythronolide-B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.653
KUN42929.1
Topoisomerase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.647
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.636
KUN44700.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.634
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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