Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KUN48144.1Tat pathway signal sequence domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.820
KUN46643.1
Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.649
KUN48143.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.608
KUN43334.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.557
KUN49094.1
Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
KUN47830.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
KUN43678.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
KUN43679.1
Diaminohydroxyphosphoribosylaminopyrimidine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
KUN43680.1
Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
KUN41391.1
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.528
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.