Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN47287.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
       0.827
KUN47702.1
DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.809
KUN42310.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.771
KUN44368.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.767
KUN47620.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.757
KUN47289.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.727
KUN47290.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.727
KUN47291.1
Molybdopterin-binding oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.650
KUN47293.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.644
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.631
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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