Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN47153.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.957
aroH_1
Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family.
   
 0.920
aroH_2
Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family.
   
 0.920
KUN47103.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
KUN47804.1
Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.906
dhbB
Phosphopantetheine attachment domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.896
mqnA
Menaquinone biosynthesis protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
  
  0.891
KUN42915.1
Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.890
trpE
Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
  
 
 0.884
trpE-2
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.884
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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