STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (589 aa)    
Predicted Functional Partners:
hemL
Glutamate-1-semialdehyde aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
hemC1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.992
KUN46643.1
Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.990
KUN42670.1
Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.983
hemB
Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
 
  
 0.972
KUN40627.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.970
hemC2
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.965
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.960
KUN47528.1
Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 
 0.947
KUN44700.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.873
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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