Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN46600.1biotin--acetyl-CoA-carboxylase ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.936
KUN46599.1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.924
KUN44992.1
acety-l/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.886
KUN40574.1
acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.886
KUN46594.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.880
KUN47392.1
Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.823
KUN38975.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.816
cya
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.801
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.778
KUN46598.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.769
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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