Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN46261.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (286 aa)    
Predicted Functional Partners:
KUN44279.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
folB
Diguanylate cyclase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.990
KUN45886.1
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.983
folE2
GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.954
folE
GTP cyclohydrolase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.951
KUN47103.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.935
KUN44276.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
0.899
KUN47904.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.853
KUN47536.1
4-amino-4-deoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.848
KUN47535.1
Chloride transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.836
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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