Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KUN45129.1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the type-B carboxylesterase/lipase family. (510 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.804
sbcC
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.625
KUN48092.1
Peptidase M14; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.617
KUN46678.1
Peptidase M28; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.595
KUN49896.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.583
KUN37927.1
Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.583
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.579
sucA
SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.579
KUN44119.1
Rhamnosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.564
KUN42899.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.535
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.