Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KUN44954.1Copper homeostasis protein CutC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CutC family. (234 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
   0.757
KUN44953.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.724
KUN45131.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.645
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.641
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.544
KUN49622.1
6-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.528
KUN44608.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.528
pgl-2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.528
KUN40585.1
beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.506
KUN41799.1
Beta-hexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.483
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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