STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alcAllantoicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the allantoicase family. (371 aa)    
Predicted Functional Partners:
allB
Cyclic amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
ureB
Urease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family.
 
  
  0.912
ureA
Urease subunit gamma; UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family.
 
  
  0.912
hyuA
Phenylhydantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.902
KUN40781.1
5-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
 
 0.878
ureC2
Urease subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.854
ureC
Urease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.854
KUN47233.1
OHCU decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.802
KUN40780.1
OHCU decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.796
KUN40782.1
Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
  
 0.788
Your Current Organism:
Streptomyces olivochromogenes
NCBI taxonomy Id: 1963
Other names: ATCC 25479, ATCC 3336, Actinomyces olivochromogenus, CBS 889.69, DSM 40451, IFO 13067, IFO 3178, IMET 40352, ISP 5451, JCM 4163, JCM 4500, KCTC 9064, NBRC 13067, NBRC 3178, NRRL-ISP 5451, S. olivochromogenes, Streptomyces olivichromogenes, Streptomyces olivochromogenus
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