STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srkAStress response serine/threonine protein kinase YihE; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (327 aa)    
Predicted Functional Partners:
ORC35318.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.816
hflX
GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
    0.782
ORC32765.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.781
ORC38332.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the uroporphyrinogen decarboxylase family.
       0.661
ORC38333.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
       0.661
ORC34869.1
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.638
ORC32940.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.633
ORC37792.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.627
ORC29874.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.602
ORC36199.1
Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.593
Your Current Organism:
Marispirochaeta aestuarii
NCBI taxonomy Id: 1963862
Other names: Candidatus Marispirochaeta sp. JC444, DSM 103365, KCTC 15554, M. aestuarii, Marispirochaeta aestuarii Shivani et al. 2017, Marispirochaeta sp. JC444, Spirochaeta sp. JC444, strain JC444
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