STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORC38440.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (379 aa)    
Predicted Functional Partners:
ORC38468.1
Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.959
ORC35316.1
Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.959
ORC38439.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.950
ORC34812.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.936
ORC31104.1
Hypothetical protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]
   
 0.923
ORC31784.1
PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.862
ORC35663.1
Amino-acid N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family.
   
 
 0.818
ORC31128.1
Acetylglutamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.803
ORC37377.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.784
ORC38441.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.757
Your Current Organism:
Marispirochaeta aestuarii
NCBI taxonomy Id: 1963862
Other names: Candidatus Marispirochaeta sp. JC444, DSM 103365, KCTC 15554, M. aestuarii, Marispirochaeta aestuarii Shivani et al. 2017, Marispirochaeta sp. JC444, Spirochaeta sp. JC444, strain JC444
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