STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORC36346.1Hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (338 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.773
rnfD
Electron transporter RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
 
  
 0.768
ORC32763.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.736
ORC35461.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit E; Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NqrDE/RnfAE family.
 
  
 0.733
ORC35328.1
Electron transporter RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.
 
  
 0.733
rnfA
Electron transport complex subunit RsxA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
  
 0.726
rnfE
Electron transport complex subunit RsxE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
 
   
 0.709
ORC35326.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit D; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NqrDE/RnfAE family.
 
  
 0.694
rnfC
Electron transport complex subunit RsxC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
 
   
 0.679
ORC36345.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.623
Your Current Organism:
Marispirochaeta aestuarii
NCBI taxonomy Id: 1963862
Other names: Candidatus Marispirochaeta sp. JC444, DSM 103365, KCTC 15554, M. aestuarii, Marispirochaeta aestuarii Shivani et al. 2017, Marispirochaeta sp. JC444, Spirochaeta sp. JC444, strain JC444
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