STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORC34318.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)    
Predicted Functional Partners:
ORC34251.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.983
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 0.955
ORC31118.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.947
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.929
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
  
 
 0.919
ORC36921.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.884
ORC37029.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.859
ORC35401.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.829
ORC34255.1
RNA polymerase sigma factor WhiG; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
 
   
 0.828
ORC34249.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.822
Your Current Organism:
Marispirochaeta aestuarii
NCBI taxonomy Id: 1963862
Other names: Candidatus Marispirochaeta sp. JC444, DSM 103365, KCTC 15554, M. aestuarii, Marispirochaeta aestuarii Shivani et al. 2017, Marispirochaeta sp. JC444, Spirochaeta sp. JC444, strain JC444
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