STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cgl0007HYPOTHETICAL PROTEIN. (322 aa)    
Predicted Functional Partners:
Cgl2455
SINGLE-STRAND DNA BINDING PROTEIN.
   
  
 0.703
gyrB
DNA GYRASE SUBUNIT B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.701
Cgl0747
Conserved hypothetical protein.
   
  
 0.610
groEL-3
Chaperonin cpn60 (60Kd subunit); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.604
groEL-2
60 KDA CHAPERONIN (PROTEIN CPN60) (GROEL PROTEIN) C-terminal fragment; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.592
Cgl2490
Bacterial regulatory protein, tetR family.
  
     0.579
Cgl0628
Secreted lipoprotein; Belongs to the calycin superfamily. Lipocalin family.
  
    0.538
Cgl0137
PUTATIVE TRANSPORT PROTEIN.
      
 0.531
Cgl0405
Hypothetical protein.
  
     0.523
Cgl1297
PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR.
      
 0.506
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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