node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
pdxK | pdxR | cg1041 | cg0897 | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | Pyridoxine biosynthesis transcriptional regulator, aminotransferase; May have a regulatory function in pyridoxine biosynthesis. Is said to also have an aminotransferase activity in valine biosynthesis as a double inactivation of ilvE and pdxR results in an auxotrophic requirement for valine; In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.747 |
pdxK | pdxS | cg1041 | cg0898 | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | 0.939 |
pdxK | pdxT | cg1041 | cg0899 | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | Glutamine amidotransferase involved in pyridoxine biosynthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.944 |
pdxK | thiD2-2 | cg1041 | cg3409 | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | PUTATIVE PHOSPHOMETHYLPYRIMIDINE KINASE. | 0.905 |
pdxR | pdxK | cg0897 | cg1041 | Pyridoxine biosynthesis transcriptional regulator, aminotransferase; May have a regulatory function in pyridoxine biosynthesis. Is said to also have an aminotransferase activity in valine biosynthesis as a double inactivation of ilvE and pdxR results in an auxotrophic requirement for valine; In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | 0.747 |
pdxR | pdxS | cg0897 | cg0898 | Pyridoxine biosynthesis transcriptional regulator, aminotransferase; May have a regulatory function in pyridoxine biosynthesis. Is said to also have an aminotransferase activity in valine biosynthesis as a double inactivation of ilvE and pdxR results in an auxotrophic requirement for valine; In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | 0.856 |
pdxR | pdxT | cg0897 | cg0899 | Pyridoxine biosynthesis transcriptional regulator, aminotransferase; May have a regulatory function in pyridoxine biosynthesis. Is said to also have an aminotransferase activity in valine biosynthesis as a double inactivation of ilvE and pdxR results in an auxotrophic requirement for valine; In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Glutamine amidotransferase involved in pyridoxine biosynthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.729 |
pdxS | pdxK | cg0898 | cg1041 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | 0.939 |
pdxS | pdxR | cg0898 | cg0897 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | Pyridoxine biosynthesis transcriptional regulator, aminotransferase; May have a regulatory function in pyridoxine biosynthesis. Is said to also have an aminotransferase activity in valine biosynthesis as a double inactivation of ilvE and pdxR results in an auxotrophic requirement for valine; In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.856 |
pdxS | pdxT | cg0898 | cg0899 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | Glutamine amidotransferase involved in pyridoxine biosynthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.999 |
pdxS | prsA | cg0898 | cg1075 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE ISOZYME 2 PR; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.807 |
pdxS | rbsK1 | cg0898 | cg1546 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | PUTATIVE RIBOKINASE PROTEIN; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.810 |
pdxS | rbsK2 | cg0898 | cg2554 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | PROBABLE RIBOKINASE PROTEIN; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.810 |
pdxS | rpi | cg0898 | cg2658 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | POSSIBLE PHOSPHOPENTOSE ISOMERASE. | 0.800 |
pdxS | tal | cg0898 | cg1776 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | TRANSALDOLASE; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.818 |
pdxS | thiD2-2 | cg0898 | cg3409 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | PUTATIVE PHOSPHOMETHYLPYRIMIDINE KINASE. | 0.909 |
pdxS | tkt | cg0898 | cg1774 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | TRANSKETOLASE; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.810 |
pdxT | pdxK | cg0899 | cg1041 | Glutamine amidotransferase involved in pyridoxine biosynthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | PYRIDOXAL/PYRIDOXINE/PYRIDOXAMINE KINASE; Belongs to the pyridoxine kinase family. | 0.944 |
pdxT | pdxR | cg0899 | cg0897 | Glutamine amidotransferase involved in pyridoxine biosynthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | Pyridoxine biosynthesis transcriptional regulator, aminotransferase; May have a regulatory function in pyridoxine biosynthesis. Is said to also have an aminotransferase activity in valine biosynthesis as a double inactivation of ilvE and pdxR results in an auxotrophic requirement for valine; In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.729 |
pdxT | pdxS | cg0899 | cg0898 | Glutamine amidotransferase involved in pyridoxine biosynthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. | 0.999 |