STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ripAAraC-type DNA-binding domain-containing protein; Under iron limitation, RipA negatively controls the expression of the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes. Binds to the consensus sequence in the promoter region. (331 aa)    
Predicted Functional Partners:
dtxR
IRON DEPENDENT REGULATORY PROTEIN-DTXR HOMOLOG; Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression (By similarity). Represses ripA under iron excess.
   
  
 0.965
irp1
DTXR/IRON REGULATED LIPOPROTEIN PRECURSOR, secrete.
   
  
 0.903
Cgl0501
cobalamin/Fe3+-siderophores transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
   
    0.902
Cgl0808
ABC-type cobalamin/Fe3+-siderophores transport system, secreted component.
   
  
 0.891
Cgl1258
Putative Na+-dependent transporter.
   
    0.882
Cgl1257
ABC-type cobalamin/Fe3+-siderophores transport system secreted component.
   
  
 0.881
Cgl0665
Siderophore-interacting protein.
  
  
 0.879
Cgl0502
cobalamin/Fe3+-siderophores transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
   
    0.863
Cgl0668
ABC-type cobalamin/Fe3+-siderophores transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
   
    0.863
Cgl0392
Conserved secreted protein.
   
    0.860
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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