node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0208 | thiC | cg0257 | cg1476 | HESA/MOEB/THIF FAMILY PROTEIN. | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.707 |
Cgl0208 | thiD1 | cg0257 | cg1654 | HESA/MOEB/THIF FAMILY PROTEIN. | PHOSPHOMETHYLPYRIMIDINE KINASE / HYDROXYMETHYLPYRI; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). In the N-terminal section; belongs to the thiamine- phosphate synthase family. In the C-terminal section; belongs to the thiaminase-2 family. | 0.968 |
Cgl0208 | thiD2 | cg0257 | cg3400 | HESA/MOEB/THIF FAMILY PROTEIN. | PUTATIVE PHOSPHOMETHYLPYRIMIDINE KINASE (C-terminal fragment). | 0.496 |
Cgl0208 | thiD2-2 | cg0257 | cg3409 | HESA/MOEB/THIF FAMILY PROTEIN. | PUTATIVE PHOSPHOMETHYLPYRIMIDINE KINASE. | 0.496 |
Cgl0208 | thiE | cg0257 | cg2236 | HESA/MOEB/THIF FAMILY PROTEIN. | THIAMIN-PHOSPHATE PYROPHOSPHORYLASE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.557 |
Cgl0208 | thiF | cg0257 | cg2240 | HESA/MOEB/THIF FAMILY PROTEIN. | Dinucleotide-utilizing enzyme involved in thiamine biosynthesis. | 0.935 |
Cgl0208 | thiG | cg0257 | cg2239 | HESA/MOEB/THIF FAMILY PROTEIN. | THIAMIN BIOSYNTHESIS PROTEIN; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.867 |
Cgl0781 | thiC | cg0890 | cg1476 | Conserved hypothetical protein. | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.479 |
Cgl0781 | thiD1 | cg0890 | cg1654 | Conserved hypothetical protein. | PHOSPHOMETHYLPYRIMIDINE KINASE / HYDROXYMETHYLPYRI; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). In the N-terminal section; belongs to the thiamine- phosphate synthase family. In the C-terminal section; belongs to the thiaminase-2 family. | 0.946 |
Cgl0781 | thiG | cg0890 | cg2239 | Conserved hypothetical protein. | THIAMIN BIOSYNTHESIS PROTEIN; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.534 |
thiC | Cgl0208 | cg1476 | cg0257 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | HESA/MOEB/THIF FAMILY PROTEIN. | 0.707 |
thiC | Cgl0781 | cg1476 | cg0890 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Conserved hypothetical protein. | 0.479 |
thiC | thiD1 | cg1476 | cg1654 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | PHOSPHOMETHYLPYRIMIDINE KINASE / HYDROXYMETHYLPYRI; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). In the N-terminal section; belongs to the thiamine- phosphate synthase family. In the C-terminal section; belongs to the thiaminase-2 family. | 0.997 |
thiC | thiD2 | cg1476 | cg3400 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | PUTATIVE PHOSPHOMETHYLPYRIMIDINE KINASE (C-terminal fragment). | 0.632 |
thiC | thiD2-2 | cg1476 | cg3409 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | PUTATIVE PHOSPHOMETHYLPYRIMIDINE KINASE. | 0.638 |
thiC | thiE | cg1476 | cg2236 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | THIAMIN-PHOSPHATE PYROPHOSPHORYLASE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.993 |
thiC | thiF | cg1476 | cg2240 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Dinucleotide-utilizing enzyme involved in thiamine biosynthesis. | 0.881 |
thiC | thiG | cg1476 | cg2239 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | THIAMIN BIOSYNTHESIS PROTEIN; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.978 |
thiC | thiL | cg1476 | cg1495 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | THIAMINE-MONOPHOSPHATE KINASE; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.465 |
thiC | thiM | cg1476 | cg1655 | THIAMINE BIOSYNTHESIS PROTEIN; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | HYDROXYETHYLTHIAZOLE KINASE; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.867 |