STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cgl2116DNA polymerase III epsilon subunit or related 3'-5' exonuclease. (476 aa)    
Predicted Functional Partners:
dnaN
DNA POLYMERASE III, BETA SUBUNIT; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.968
dnaZX
DNA POLYMERASE III GAMMA AND TAU SUBUNITS; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.967
dnaE1
PUTATIVE DNA POLYMERASE III, ALPHA CHAIN.
  
 0.955
Cgl2346
Putative DNA polymerase III delta subunit.
   
 0.945
dnaX
PUTATIVE DNA POLYMERASE III, DELTA' SUBUNIT.
  
 0.935
polA
DNA POLYMERASE I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.920
Cgl0779
PUTATIVE DNA HELICASE RECQ.
 
  
 0.918
Cgl0247
DNA polymerase III epsilon subunit or related 3'-5' exonuclease.
 
  
 0.917
Cgl1243
Putative DNA polymerase III alpha subunit, the Gram-positive type.
 
  
 0.917
dnaQ2
DNA POLYMERASE III, EPSILON SUBUNIT, PUTATIVE.
    
 0.903
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.