node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl2910 | aceE | cg3218 | cg2466 | PYRUVATE KINASE-LIKE PROTEIN. | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | 0.920 |
Cgl2910 | ilvB | cg3218 | cg1435 | PYRUVATE KINASE-LIKE PROTEIN. | ACETOLACTATE SYNTHASE. | 0.817 |
Cgl2910 | ldh | cg3218 | cg3219 | PYRUVATE KINASE-LIKE PROTEIN. | L-LACTATE DEHYDROGENASE; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.989 |
Cgl2910 | lldA | cg3218 | cg3227 | PYRUVATE KINASE-LIKE PROTEIN. | PUTATIVE L-LACTATE DEHYDROGENASE. | 0.933 |
Cgl2910 | poxB | cg3218 | cg2891 | PYRUVATE KINASE-LIKE PROTEIN. | PYRUVATE DEHYDROGENASE; Belongs to the TPP enzyme family. | 0.919 |
Cgl2910 | pyc | cg3218 | cg0791 | PYRUVATE KINASE-LIKE PROTEIN. | PYRUVATE CARBOXYLASE; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.943 |
Cgl2910 | pyk | cg3218 | cg2291 | PYRUVATE KINASE-LIKE PROTEIN. | PYRUVATE KINASE. | 0.945 |
aceE | Cgl2910 | cg2466 | cg3218 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | PYRUVATE KINASE-LIKE PROTEIN. | 0.920 |
aceE | ilvB | cg2466 | cg1435 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | ACETOLACTATE SYNTHASE. | 0.925 |
aceE | ldh | cg2466 | cg3219 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | L-LACTATE DEHYDROGENASE; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.970 |
aceE | lldA | cg2466 | cg3227 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | PUTATIVE L-LACTATE DEHYDROGENASE. | 0.935 |
aceE | lpd | cg2466 | cg0441 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | DIHYDROLIPOAMIDE DEHYDROGENASE; Lipoamide dehydrogenase is an essential component of the pyruvate dehydrogenase (PDH) and 2-oxoglutarate dehydrogenase (ODH) complexes. Catalyzes the reoxidation of dihydrolipoyl groups which are covalently attached to the lipoate acyltransferase components (E2) of the complexes. Also catalyzes a reversible NADH:NAD(+) transhydrogenation, and is able to transfer electrons from NADH to various redox-active compounds and quinones. May be involved in quinone redox cycling in C.glutamicum. | 0.996 |
aceE | odhA | cg2466 | cg1280 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | 2-OXOGLUTARATE DEHYDROGENASE; Catalyzes the E1 and E2 reactions as part of 2-oxoglutarate dehydrogenase (ODH) activity, to convert 2-oxoglutarate to succinyl-CoA and CO(2). OdhA has reductase activity with 2-oxoglutarate but does not react with pyruvate, and also displays transsuccinylase but no transacetylase activity. Since OdhA is not lipoylated, the succinyltransferase activity of its E2 domain is dependent on lipoyl residues of the acetyltransferase AceF. | 0.969 |
aceE | poxB | cg2466 | cg2891 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | PYRUVATE DEHYDROGENASE; Belongs to the TPP enzyme family. | 0.935 |
aceE | pyc | cg2466 | cg0791 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | PYRUVATE CARBOXYLASE; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.962 |
aceE | pyk | cg2466 | cg2291 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | PYRUVATE KINASE. | 0.947 |
aceE | sucB | cg2466 | cg2421 | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE; Is essential for both 2-oxoglutarate dehydrogenase (ODH) and pyruvate dehydrogenase (PDH) activities, but AceF has exclusively transacetylase (and no transsuccinylase) activity. The lipoyl residues required for ODH activity are likely provided by AceF. Belongs to the 2-oxoacid dehydrogenase family. | 0.996 |
ilvB | Cgl2910 | cg1435 | cg3218 | ACETOLACTATE SYNTHASE. | PYRUVATE KINASE-LIKE PROTEIN. | 0.817 |
ilvB | aceE | cg1435 | cg2466 | ACETOLACTATE SYNTHASE. | PYRUVATE DEHYDROGENASE E1 COMPONENT; Is a specific component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl- CoA and CO(2). AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate. | 0.925 |
ilvB | ldh | cg1435 | cg3219 | ACETOLACTATE SYNTHASE. | L-LACTATE DEHYDROGENASE; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.879 |