node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cgl0052 | Cgl1310 | cg0071 | cg1482 | Metallo-beta-lactamase superfamily. | Zn-dependent hydrolases, including glyoxylases. | 0.961 |
Cgl0052 | ybeY | cg0071 | cg2512 | Metallo-beta-lactamase superfamily. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.966 |
Cgl1310 | Cgl0052 | cg1482 | cg0071 | Zn-dependent hydrolases, including glyoxylases. | Metallo-beta-lactamase superfamily. | 0.961 |
Cgl1310 | ybeY | cg1482 | cg2512 | Zn-dependent hydrolases, including glyoxylases. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.966 |
Cgl1636 | ybeY | cg1842 | cg2512 | Putative secreted metalloprotease. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.982 |
Cgl2286 | bex | cg2511 | cg2510 | Putative membrane protein containing CBS domain. | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.847 |
Cgl2286 | dnaJ2 | cg2511 | cg2515 | Putative membrane protein containing CBS domain. | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | 0.771 |
Cgl2286 | phoH2 | cg2511 | cg2513 | Putative membrane protein containing CBS domain. | Phosphate starvation-inducible protein. | 0.855 |
Cgl2286 | ybeY | cg2511 | cg2512 | Putative membrane protein containing CBS domain. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.899 |
bex | Cgl2286 | cg2510 | cg2511 | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Putative membrane protein containing CBS domain. | 0.847 |
bex | dnaJ2 | cg2510 | cg2515 | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | 0.697 |
bex | phoH2 | cg2510 | cg2513 | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Phosphate starvation-inducible protein. | 0.918 |
bex | ybeY | cg2510 | cg2512 | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.927 |
dnaJ2 | Cgl2286 | cg2515 | cg2511 | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | Putative membrane protein containing CBS domain. | 0.771 |
dnaJ2 | bex | cg2515 | cg2510 | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | BEX PROTEIN (GTP-BINDING PROTEIN ERA HOMOLOG); An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.697 |
dnaJ2 | phoH2 | cg2515 | cg2513 | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | Phosphate starvation-inducible protein. | 0.724 |
dnaJ2 | ybeY | cg2515 | cg2512 | Molecular chaperone (contain C-terminal Zn finger domain), putative transcriptional repressor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the react [...] | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.892 |
gpsI | rnj | cg2166 | cg2160 | PUTATIVE POLYRIBONUCLEOTIDE PHOSPHORYLASE / GUANOSINE PENTAPHOSPHATESYNTHETASE; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | HYDROLASE OF METALLO-BETA-LACTAMASE SUPERFAMILY; An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. | 0.991 |
gpsI | rph | cg2166 | cg2753 | PUTATIVE POLYRIBONUCLEOTIDE PHOSPHORYLASE / GUANOSINE PENTAPHOSPHATESYNTHETASE; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | PROBABLE RIBONUCLEASE PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.877 |
gpsI | ybeY | cg2166 | cg2512 | PUTATIVE POLYRIBONUCLEOTIDE PHOSPHORYLASE / GUANOSINE PENTAPHOSPHATESYNTHETASE; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.984 |