STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brnQBranched-Chain Amino Acid Uptake Carrier; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force. (426 aa)    
Predicted Functional Partners:
aecD
Cystathionine beta-Lyase.
  
  
 0.880
Cgl2311
ALKANAL MONOOXYGENASE ALPHA CHAIN.
  
    0.726
putP
PROLINE TRANSPORT SYSTEM; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.687
Cgl2308
Putative secreted protein.
  
    0.658
lysE
Lysine efflux permease; Catalyzes the efflux of L-lysine. Can also export L- arginine and L-citrulline. The lysEG system prevents bacteriostasis due to elevated L-lysine or L-arginine concentrations that arise during growth in the presence of peptides or in mutants possessing a deregulated biosynthesis pathway. In vitro, can also export D-lysine during biotechnological production of D-amino acids.
      
 0.639
ilvB
ACETOLACTATE SYNTHASE.
      
 0.639
ilvA
THREONINE DEHYDRATASE; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity).
   
  
 0.620
argF
ORNITHINE CARBAMOYLTRANSFERASE; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
   
  
 0.618
proB
GLUTAMATE 5-KINASE PROTEIN; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
  
 0.611
aroP
AROMATIC AMINO ACID TRANSPORT PROTEIN; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
   
  
 0.580
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.