STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purBADENYLOSUCCINATE LYASE; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (476 aa)    
Predicted Functional Partners:
purA
ADENYLOSUCCINATE SYNTHETASE; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.999
purH
5'-PHOSPHORIBOSYL-5-AMINOIMIDAZOLE-4- CARBOXYLASE.
  
 0.990
purC
PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE; Belongs to the SAICAR synthetase family.
  
 0.989
apt
ADENINE PHOSPHORIBOSYLTRANSFERASE; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.979
adk
ADENYLATE KINASE; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.975
purD
PHOSPHORIBOSYLAMINE-GLYCINE LIGASE.
  
 
 0.948
guaA
PUTATIVE GMP SYNTHASE; Catalyzes the synthesis of GMP from XMP.
 
  
 0.940
argH
ARGININOSUCCINATE LYASE.
  
 
 0.914
Cgl0328
PROBABLE 5'-NUCLEOTIDASE PRECURSOR; Belongs to the 5'-nucleotidase family.
   
 
 0.902
aspA
ASPARTATE AMMONIA-LYASE (ASPARTASE).
     
 0.901
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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