STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panC2SIMILAR TO PANTOTHENATE SYNTHETASE. (266 aa)    
Predicted Functional Partners:
panB
3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.998
panD
ASPARTATE 1-DECARBOXYLASE; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.997
coaA
PANTOTHENATE KINASE.
   
 
 0.961
panC
PANTOATE--BETA-ALANINE LIGASE PROTEIN; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
  
0.930
Cgl1089
SIMILAR TO KETOPANTOATE REDUCTASE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
  
 0.927
gabT
PROBABLE 4-AMINOBUTYRATE AMINOTRANSFERASE PROTEIN; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.901
betB
PUTATIVE BETAINE ALDEHYDE DEHYDROGENASE (BADH) OXIDOREDUCTASE.
   
 
  0.900
Cgl2441
Aminotransferase class-III, pyridoxal-phosphate dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.900
xylC
BENZALDEHYDE DEHYDROGENASE; Belongs to the aldehyde dehydrogenase family.
     
  0.900
dfp
DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.858
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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