STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAACETATE KINASE; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. (397 aa)    
Predicted Functional Partners:
pta
PHOSPHATE ACETYLTRANSFERASE; Belongs to the phosphate acetyltransferase and butyryltransferase family.
 
 
 0.999
aceA
ISOCITRATE LYASE; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
   
  
 0.986
poxB
PYRUVATE DEHYDROGENASE; Belongs to the TPP enzyme family.
    
 0.984
aceB
MALATE SYNTHASE; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
  
 0.976
actA
BUTYRYL-COA:ACETATE COENZYME A TRANSFERASE.
   
 
 0.963
Cgl2796
ALDEHYDE DEHYDROGENASE; Belongs to the aldehyde dehydrogenase family.
 
 
 0.939
acyP
PUTATIVE ACYLPHOSPHATASE.
     
 0.935
betB
PUTATIVE BETAINE ALDEHYDE DEHYDROGENASE (BADH) OXIDOREDUCTASE.
 
 
 0.912
xylC
BENZALDEHYDE DEHYDROGENASE; Belongs to the aldehyde dehydrogenase family.
 
 
 0.912
pyc
PYRUVATE CARBOXYLASE; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
  
 0.907
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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