STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cgl2844Aminotransferases class-I. (437 aa)    
Predicted Functional Partners:
ilvE
BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE.
  
 
 0.932
ilvD
DIHYDROXY-ACID DEHYDRATASE; Belongs to the IlvD/Edd family.
   
 
 0.914
gdh
NADP-SPECIFIC GLUTAMATE DEHYDROGENASE; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
  
 
 0.910
leuA
2-ISOPROPYLMALATE SYNTHASE; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.906
argJ
GLUTAMATE N-ACETYLTRANSFERASE; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
   
 
 0.905
Cgl2740
Acetyltransferase.
     
  0.900
odhA
2-OXOGLUTARATE DEHYDROGENASE; Catalyzes the E1 and E2 reactions as part of 2-oxoglutarate dehydrogenase (ODH) activity, to convert 2-oxoglutarate to succinyl-CoA and CO(2). OdhA has reductase activity with 2-oxoglutarate but does not react with pyruvate, and also displays transsuccinylase but no transacetylase activity. Since OdhA is not lipoylated, the succinyltransferase activity of its E2 domain is dependent on lipoyl residues of the acetyltransferase AceF.
   
 0.852
alr
ALANINE RACEMASE; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
    
 0.815
fum
FUMARATE HYDRATASE; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.815
icd
ISOCITRATE DEHYDROGENASE; Belongs to the monomeric-type IDH family.
 
 
 
  0.813
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.