STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cgl3026Aromatic-ring hydroxylase (flavoprotein monooxygenase); Catalyzes the NADH-dependent conversion of 3-hydroxybenzoate to gentisate (2,5-dihydroxybenzoate). Is involved in the utilization of 3-hydroxybenzoate as a sole source of carbon and energy for C.glutamicum growth. Displays a high preference for NADH over NADPH as cosubstrate. Is not active with 4-hydroxybenzoate, salicylate, protocatechuate or benzoate as substrates. (442 aa)    
Predicted Functional Partners:
nagI
PROBABLE GENTISATE 1,2-DIOXYGENASE OXIDOREDUCTASE.
 
  
 0.963
Cgl3021
Conserved hypothetical protein.
 
   
 0.948
Cgl0967
Predicted esterase, membrane protein.
   
  
 0.797
benK2
Putative benzoate transport protein; Transport of gentisate (2,5-dihydroxybenzoate) into the cell. Does not transport 3-hydroxybenzoate or benzoate. Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
 
    0.732
bglS
BETA-GLUCOSIDASE PRECURSOR-N-terminal domain.
  
   
 0.708
Cgl3024
Transcriptional regulator; Unnamed protein product.
 
  
 0.659
Cgl1439
Hydrolase of the alpha/beta superfamily.
   
  
 0.638
scoA
PROBABLE FESUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE SUBUNIT.
     
 0.589
aroF
PROBABLE PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
      
 0.464
cytP
CYTOCHROME P450.
  
 
 0.426
Your Current Organism:
Corynebacterium glutamicum
NCBI taxonomy Id: 196627
Other names: C. glutamicum ATCC 13032, Corynebacterium glutamicum ATCC 13032, Corynebacterium glutamicum str. ATCC 13032, Corynebacterium glutamicum strain ATCC 13032
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