OQX83468.1 protein (candidate division KSB1)

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

OQX83468.1

ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)

Predicted Functional Partners:

OQX82824.1

0.971

OQX83467.1

0.923

OQX82871.1

0.852

OQX86264.1

0.851

OQX87803.1

0.800

OQX85245.1

0.800

B6D60_05395

0.784

OQX82827.1

0.718

OQX83140.1

0.648

OQX83154.1

0.600

Your Current Organism:

candidate division KSB1

NCBI taxonomy Id: 1970772
Other names: c. division KSB1 bacterium 4484_87, candidate division KSB1 bacterium 4484_87

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B6D60_05395	OQX83468.1	B6D60_05395	B6D60_10445	Hypothetical protein; Metagenomic; derived from metagenome: marine sediment metagenome.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.784
OQX82824.1	OQX82827.1	B6D60_11530	B6D60_11545	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.487
OQX82824.1	OQX83468.1	B6D60_11530	B6D60_10445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
OQX82827.1	OQX82824.1	B6D60_11545	B6D60_11530	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.487
OQX82827.1	OQX83468.1	B6D60_11545	B6D60_10445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.718
OQX82871.1	OQX83468.1	B6D60_11430	B6D60_10445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.852
OQX83140.1	OQX83468.1	B6D60_11005	B6D60_10445	Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.648
OQX83154.1	OQX83468.1	B6D60_10900	B6D60_10445	F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.600
OQX83467.1	OQX83468.1	B6D60_10440	B6D60_10445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
OQX83468.1	B6D60_05395	B6D60_10445	B6D60_05395	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Metagenomic; derived from metagenome: marine sediment metagenome.	0.784
OQX83468.1	OQX82824.1	B6D60_10445	B6D60_11530	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
OQX83468.1	OQX82827.1	B6D60_10445	B6D60_11545	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.718
OQX83468.1	OQX82871.1	B6D60_10445	B6D60_11430	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.852
OQX83468.1	OQX83140.1	B6D60_10445	B6D60_11005	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Macrolide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.648
OQX83468.1	OQX83154.1	B6D60_10445	B6D60_10900	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.600
OQX83468.1	OQX83467.1	B6D60_10445	B6D60_10440	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
OQX83468.1	OQX85245.1	B6D60_10445	B6D60_08195	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.800
OQX83468.1	OQX86264.1	B6D60_10445	B6D60_06575	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.851
OQX83468.1	OQX87803.1	B6D60_10445	B6D60_03230	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.800
OQX85245.1	OQX83468.1	B6D60_08195	B6D60_10445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.800

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Network Stats

number of nodes:

11

number of edges:

28

average node degree:

5.09

avg. local clustering coefficient:

0.794

expected number of edges:

16

PPI enrichment p-value:

0.00371

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051537

2 iron, 2 sulfur cluster binding

5 of 22

1.81

2.24

9.19e-06

GO:0016491

Oxidoreductase activity

8 of 384

0.78

0.62

0.0015

GO:0043167

Ion binding

9 of 811

0.5

0.35

0.0186

GO:0005488

Binding

11 of 1306

0.38

0.3

0.0085

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2121

Mixed, incl. AMP-binding enzyme C-terminal domain, and 2Fe-2S

7 of 28

1.86

3.45

2.49e-09

CL:2124

Mixed, incl. Cytochrome P450, and Phosphopantetheine

5 of 11

2.11

3.14

2.72e-07

CL:2126

Phosphopantetheine, and Oxidoreductase NAD-binding domain

4 of 5

2.36

3.03

1.31e-06

CL:1521

Glutamate synthase activity, and Gas transport

2 of 6

1.98

0.8

0.0314

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00360

Phenylalanine metabolism

3 of 29

1.47

0.81

0.0192

map01120

Microbial metabolism in diverse environments

6 of 342

0.7

0.42

0.0317

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0001

2Fe-2S

5 of 10

2.16

3.36

1.06e-07

KW-0408

Iron

6 of 61

1.45

1.87

3.13e-06

KW-0596

Phosphopantetheine

2 of 3

2.28

1.26

0.0045

KW-0479

Metal-binding

6 of 219

0.9

0.71

0.0021

KW-0349

Heme

2 of 13

1.64

0.71

0.0385

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00111

2Fe-2S iron-sulfur cluster binding domain

5 of 10

2.16

3.19

2.62e-07

PF00970

Oxidoreductase FAD-binding domain

4 of 4

2.46

3.06

1.39e-06

PF00175

Oxidoreductase NAD-binding domain

4 of 4

2.46

3.06

1.39e-06

PF00550

Phosphopantetheine attachment site

2 of 3

2.28

1.01

0.0138

PF00067

Cytochrome P450

2 of 3

2.28

1.01

0.0138

(more ...)

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