OQY35691.1 protein (Spirochaetaceae bacterium 457259)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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[Homology]

Score

OQY35691.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)

Predicted Functional Partners:

OQY33245.1

0.958

OQY32534.1

0.784

OQY32434.1

0.782

OQY35259.1

0.780

OQY35690.1

0.779

OQY32144.1

0.773

OQY32442.1

0.771

OQY33797.1

0.607

OQY35692.1

0.455

OQY35649.1

0.443

Your Current Organism:

Spirochaetaceae bacterium 457259

NCBI taxonomy Id: 1971727
Other names: S. bacterium 4572_59, Spirochaetaceae bacterium 4572_59

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OQY32144.1	OQY32434.1	B6241_11965	B6241_10990	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.420
OQY32144.1	OQY32534.1	B6241_11965	B6241_10660	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.473
OQY32144.1	OQY33245.1	B6241_11965	B6241_08215	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
OQY32144.1	OQY35649.1	B6241_11965	B6241_00205	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Glycerol-3-phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.406
OQY32144.1	OQY35691.1	B6241_11965	B6241_00425	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
OQY32434.1	OQY32144.1	B6241_10990	B6241_11965	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.420
OQY32434.1	OQY32442.1	B6241_10990	B6241_11030	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.576
OQY32434.1	OQY32534.1	B6241_10990	B6241_10660	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.479
OQY32434.1	OQY33245.1	B6241_10990	B6241_08215	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
OQY32434.1	OQY35649.1	B6241_10990	B6241_00205	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Glycerol-3-phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.414
OQY32434.1	OQY35691.1	B6241_10990	B6241_00425	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.782
OQY32442.1	OQY32434.1	B6241_11030	B6241_10990	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.576
OQY32442.1	OQY32534.1	B6241_11030	B6241_10660	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.477
OQY32442.1	OQY33245.1	B6241_11030	B6241_08215	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.961
OQY32442.1	OQY35691.1	B6241_11030	B6241_00425	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.771
OQY32534.1	OQY32144.1	B6241_10660	B6241_11965	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.473
OQY32534.1	OQY32434.1	B6241_10660	B6241_10990	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.479
OQY32534.1	OQY32442.1	B6241_10660	B6241_11030	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Polyamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.477
OQY32534.1	OQY33245.1	B6241_10660	B6241_08215	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
OQY32534.1	OQY35649.1	B6241_10660	B6241_00205	Molybdenum ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glycerol-3-phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.	0.421

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Network Stats

number of nodes:

11

number of edges:

23

average node degree:

4.18

avg. local clustering coefficient:

0.847

expected number of edges:

12

PPI enrichment p-value:

0.0024

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 82

0.99

1.14

4.10e-07

GO:0044238

Primary metabolic process

11 of 345

0.41

0.35

0.00096

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 42

1.24

1.72

4.07e-08

GO:0019843

rRNA binding

7 of 35

1.21

1.4

7.60e-06

GO:0003676

Nucleic acid binding

8 of 174

0.57

0.4

0.0126

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 45

1.3

2.23

1.37e-12

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:77

Ribosome, and Translation regulator activity

11 of 61

1.16

1.73

6.99e-11

CL:79

Ribosome, and Translation regulator activity

9 of 53

1.14

1.51

2.38e-08

CL:80

Ribosome, and Translation regulator activity

6 of 39

1.1

1.11

6.69e-05

CL:158

rRNA binding

3 of 13

1.27

0.83

0.0100

CL:129

Structural constituent of ribosome, and RF-1 domain

3 of 13

1.27

0.83

0.0100

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 45

1.25

1.95

2.23e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 29

1.4

2.33

7.21e-10

GOCC:0022626

Cytosolic ribosome

5 of 10

1.61

2.07

5.09e-06

GOCC:0044391

Ribosomal subunit

5 of 14

1.46

1.73

1.65e-05

GOCC:0043229

Intracellular organelle

11 of 80

1.05

1.38

7.21e-10

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 7

1.54

1.22

0.0018

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 45

1.21

1.67

2.60e-08

KW-0687

Ribonucleoprotein

9 of 45

1.21

1.67

2.60e-08

KW-0699

rRNA-binding

7 of 32

1.25

1.56

1.61e-06

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