STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derRibosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (457 aa)    
Predicted Functional Partners:
cmk-2
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.986
OQY33679.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.912
gpsA
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.877
OQY35178.1
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
     
 0.815
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.785
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
  
 0.781
OQY35176.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.746
OQY31508.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.715
OQY34855.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.700
OQY33696.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.700
Your Current Organism:
Spirochaetaceae bacterium 457259
NCBI taxonomy Id: 1971727
Other names: S. bacterium 4572_59, Spirochaetaceae bacterium 4572_59
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