STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaJ-4DnaJ protein; ORF_ID:tll2149. (326 aa)    
Predicted Functional Partners:
dnaK3
DnaK protein 3; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 0.973
dnaK2
DnaK protein 2; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.934
dnaK1
Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.927
grpE
Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]
  
 
 0.910
tll2215
ORF_ID:tll2215; similar to DnaK protein; Belongs to the heat shock protein 70 family.
  
 0.910
tll2148
acyl-CoA dehydrogenase family protein; ORF_ID:tll2148.
  
    0.777
htpG
Heat shock protein; Molecular chaperone. Has ATPase activity.
   
 0.774
rpl17
50S ribosomal protein L17; ORF_ID:tlr0106.
  
   0.628
tll2147
N-methylpurine-DNA glycosirase; ORF_ID:tll2147; Belongs to the DNA glycosylase MPG family.
       0.628
rpl15
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.617
Your Current Organism:
Thermosynechococcus elongatus
NCBI taxonomy Id: 197221
Other names: T. elongatus BP-1, Thermosynechococcus elongatus BP-1, Thermosynechococcus elongatus IAM M-273, Thermosynechococcus elongatus NIES-2133, Thermosynechococcus elongatus str. BP-1, Thermosynechococcus elongatus strain BP-1
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