node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hisH | purD | gene:10748136 | gene:10748445 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | Glycinamide ribonucleotide synthetase; ORF_ID:tlr1839; Belongs to the GARS family. | 0.853 |
hisH | tll0523 | gene:10748136 | gene:10747112 | Amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | D-alanine:D-alanine ligase; Cell wall formation. | 0.879 |
murC | murD | gene:10746957 | gene:10746651 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.998 |
murC | murF | gene:10746957 | gene:10748154 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.987 |
murC | murG | gene:10746957 | gene:10748414 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.991 |
murC | tll0370 | gene:10746957 | gene:10746956 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. | 0.999 |
murC | tll0460 | gene:10746957 | gene:10747049 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.729 |
murC | tll0523 | gene:10746957 | gene:10747112 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | D-alanine:D-alanine ligase; Cell wall formation. | 0.977 |
murC | tlr0136 | gene:10746957 | gene:10746716 | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | ORF_ID:tlr0136; hypothetical protein. | 0.884 |
murD | murC | gene:10746651 | gene:10746957 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
murD | murF | gene:10746651 | gene:10748154 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
murD | murG | gene:10746651 | gene:10748414 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.988 |
murD | tll0370 | gene:10746651 | gene:10746956 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. | 0.979 |
murD | tll0460 | gene:10746651 | gene:10747049 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.744 |
murD | tll0523 | gene:10746651 | gene:10747112 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | D-alanine:D-alanine ligase; Cell wall formation. | 0.803 |
murD | tlr0136 | gene:10746651 | gene:10746716 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | ORF_ID:tlr0136; hypothetical protein. | 0.904 |
murF | murC | gene:10748154 | gene:10746957 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.987 |
murF | murD | gene:10748154 | gene:10746651 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.996 |
murF | murG | gene:10748154 | gene:10748414 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.990 |
murF | tll0370 | gene:10748154 | gene:10746956 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | UDP-N-acetylenolpyruvylglucosamine reductase; Cell wall formation. | 0.974 |