node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
crtE | shc | gene:10746598 | gene:10748927 | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | Squalene-hopene-cyclase; ORF_ID:tlr2309. | 0.827 |
crtE | tll0500 | gene:10746598 | gene:10747089 | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | Isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.696 |
crtE | tll0623 | gene:10746598 | gene:10747212 | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | 1-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.967 |
crtE | tlr1040 | gene:10746598 | gene:10747633 | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.648 |
crtE | tlr1041 | gene:10746598 | gene:10747634 | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.982 |
crtE | tlr2035 | gene:10746598 | gene:10748644 | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.784 |
pdxJ | tll0623 | gene:10747430 | gene:10747212 | Pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 1-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.631 |
shc | crtE | gene:10748927 | gene:10746598 | Squalene-hopene-cyclase; ORF_ID:tlr2309. | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | 0.827 |
shc | tll0500 | gene:10748927 | gene:10747089 | Squalene-hopene-cyclase; ORF_ID:tlr2309. | Isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.586 |
shc | tll0623 | gene:10748927 | gene:10747212 | Squalene-hopene-cyclase; ORF_ID:tlr2309. | 1-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.893 |
shc | tlr0605 | gene:10748927 | gene:10747195 | Squalene-hopene-cyclase; ORF_ID:tlr2309. | 4-Diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.589 |
shc | tlr1040 | gene:10748927 | gene:10747633 | Squalene-hopene-cyclase; ORF_ID:tlr2309. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.833 |
shc | tlr1041 | gene:10748927 | gene:10747634 | Squalene-hopene-cyclase; ORF_ID:tlr2309. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.883 |
shc | tlr2035 | gene:10748927 | gene:10748644 | Squalene-hopene-cyclase; ORF_ID:tlr2309. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.765 |
thiG | tll0623 | gene:10746643 | gene:10747212 | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 1-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.927 |
tll0500 | crtE | gene:10747089 | gene:10746598 | Isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Geranylgeranyl pyrophosphate synthase; ORF_ID:tll0020; Belongs to the FPP/GGPP synthase family. | 0.696 |
tll0500 | shc | gene:10747089 | gene:10748927 | Isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Squalene-hopene-cyclase; ORF_ID:tlr2309. | 0.586 |
tll0500 | tll0623 | gene:10747089 | gene:10747212 | Isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 1-deoxy-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.937 |
tll0500 | tlr0605 | gene:10747089 | gene:10747195 | Isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 4-Diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.996 |
tll0500 | tlr0996 | gene:10747089 | gene:10747588 | Isopentenyl monophosphate kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate, using ferredoxin I (PetF) as the reducing agent. | 0.955 |