node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | guaA | gene:10747417 | gene:10749038 | arginyl-tRNA-synthetase; ORF_ID:tll0826. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.988 |
argS | lysS | gene:10747417 | gene:10746793 | arginyl-tRNA-synthetase; ORF_ID:tll0826. | lysyl-tRNA synthetase; ORF_ID:tll0212; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.970 |
argS | pyrG | gene:10747417 | gene:10747359 | arginyl-tRNA-synthetase; ORF_ID:tll0826. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.820 |
argS | rpl11 | gene:10747417 | gene:10746878 | arginyl-tRNA-synthetase; ORF_ID:tll0826. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.734 |
argS | tlr2394 | gene:10747417 | gene:10749014 | arginyl-tRNA-synthetase; ORF_ID:tll0826. | Glu-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. | 0.407 |
guaA | argS | gene:10749038 | gene:10747417 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA-synthetase; ORF_ID:tll0826. | 0.988 |
guaA | lysS | gene:10749038 | gene:10746793 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | lysyl-tRNA synthetase; ORF_ID:tll0212; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.970 |
guaA | pyrG | gene:10749038 | gene:10747359 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.981 |
guaA | rpl11 | gene:10749038 | gene:10746878 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.978 |
guaA | tll0424 | gene:10749038 | gene:10747013 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Methionyl aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.971 |
guaA | tll1797 | gene:10749038 | gene:10748402 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.968 |
guaA | tll2190 | gene:10749038 | gene:10748801 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; ORF_ID:tll2190. | 0.999 |
guaA | tlr2338 | gene:10749038 | gene:10748957 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.995 |
guaA | tlr2394 | gene:10749038 | gene:10749014 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Glu-tRNA(Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. | 0.978 |
guaA | tsl1385 | gene:10749038 | gene:10747983 | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.971 |
lysS | argS | gene:10746793 | gene:10747417 | lysyl-tRNA synthetase; ORF_ID:tll0212; Belongs to the class-II aminoacyl-tRNA synthetase family. | arginyl-tRNA-synthetase; ORF_ID:tll0826. | 0.970 |
lysS | guaA | gene:10746793 | gene:10749038 | lysyl-tRNA synthetase; ORF_ID:tll0212; Belongs to the class-II aminoacyl-tRNA synthetase family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.970 |
lysS | pyrG | gene:10746793 | gene:10747359 | lysyl-tRNA synthetase; ORF_ID:tll0212; Belongs to the class-II aminoacyl-tRNA synthetase family. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.620 |
lysS | rpl11 | gene:10746793 | gene:10746878 | lysyl-tRNA synthetase; ORF_ID:tll0212; Belongs to the class-II aminoacyl-tRNA synthetase family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.694 |
pyrG | argS | gene:10747359 | gene:10747417 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | arginyl-tRNA-synthetase; ORF_ID:tll0826. | 0.820 |