node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysE | thrA | gene:10747443 | gene:10746860 | Serine acetyltransferase; ORF_ID:tlr0851. | Homoserine dehydrogenase; ORF_ID:tll0277. | 0.810 |
cysE | thrB | gene:10747443 | gene:10748370 | Serine acetyltransferase; ORF_ID:tlr0851. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.818 |
cysE | tll2390 | gene:10747443 | gene:10749010 | Serine acetyltransferase; ORF_ID:tlr0851. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.557 |
cysE | tlr1090 | gene:10747443 | gene:10747685 | Serine acetyltransferase; ORF_ID:tlr0851. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.614 |
metH | thrA | gene:10747620 | gene:10746860 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine dehydrogenase; ORF_ID:tll0277. | 0.939 |
metH | thrB | gene:10747620 | gene:10748370 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.891 |
metH | thrC | gene:10747620 | gene:10747574 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Threonine synthase; ORF_ID:tlr0982. | 0.481 |
metH | thrC-2 | gene:10747620 | gene:10747823 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.481 |
metH | tll1462 | gene:10747620 | gene:10748062 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.488 |
metH | tll2043 | gene:10747620 | gene:10748652 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Branched-chain amino acid aminotransferase; ORF_ID:tll2043. | 0.488 |
metH | tll2390 | gene:10747620 | gene:10749010 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.955 |
metH | tlr1090 | gene:10747620 | gene:10747685 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.990 |
purM | thrB | gene:10748416 | gene:10748370 | Phosphoribosyl formylglycinamidine cyclo-ligase; ORF_ID:tlr1811. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.909 |
thrA | cysE | gene:10746860 | gene:10747443 | Homoserine dehydrogenase; ORF_ID:tll0277. | Serine acetyltransferase; ORF_ID:tlr0851. | 0.810 |
thrA | metH | gene:10746860 | gene:10747620 | Homoserine dehydrogenase; ORF_ID:tll0277. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.939 |
thrA | thrB | gene:10746860 | gene:10748370 | Homoserine dehydrogenase; ORF_ID:tll0277. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.996 |
thrA | thrC | gene:10746860 | gene:10747574 | Homoserine dehydrogenase; ORF_ID:tll0277. | Threonine synthase; ORF_ID:tlr0982. | 0.727 |
thrA | thrC-2 | gene:10746860 | gene:10747823 | Homoserine dehydrogenase; ORF_ID:tll0277. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.764 |
thrA | tll1462 | gene:10746860 | gene:10748062 | Homoserine dehydrogenase; ORF_ID:tll0277. | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.872 |
thrA | tll2043 | gene:10746860 | gene:10748652 | Homoserine dehydrogenase; ORF_ID:tll0277. | Branched-chain amino acid aminotransferase; ORF_ID:tll2043. | 0.887 |