STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OKL43292.1DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (365 aa)    
Predicted Functional Partners:
OKL43293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
      0.969
OKL43294.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
OKL43295.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.667
OKL43291.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.635
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
    0.609
lon
Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
     
 0.571
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
    0.424
OKL43360.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.424
OKL43361.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.424
Your Current Organism:
Nesiotobacter exalbescens
NCBI taxonomy Id: 197461
Other names: ATCC BAA-994, CIP 108449, DSM 16456, N. exalbescens, Nesiotobacter exalbescens Donachie et al. 2006, Nesiotobacter sp. WB1-6, alpha proteobacterium LA33B, strain LA33B
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.