node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHI72648.1 | SHJ39369.1 | SAMN02745194_00951 | SAMN02745194_02449 | Chorismate mutase. | 2,3-dihydroxybenzoate-AMP ligase. | 0.708 |
SHI72648.1 | SHJ39401.1 | SAMN02745194_00951 | SAMN02745194_02450 | Chorismate mutase. | Aryl carrier domain-containing protein. | 0.717 |
SHI72648.1 | SHK18775.1 | SAMN02745194_00951 | SAMN02745194_04391 | Chorismate mutase. | Anthranilate synthase component 2. | 0.882 |
SHI72648.1 | aroC | SAMN02745194_00951 | SAMN02745194_04430 | Chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.971 |
SHI72648.1 | trpC | SAMN02745194_00951 | SAMN02745194_04393 | Chorismate mutase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.703 |
SHI72648.1 | trpD | SAMN02745194_00951 | SAMN02745194_04392 | Chorismate mutase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.703 |
SHI72648.1 | trpE | SAMN02745194_00951 | SAMN02745194_04389 | Chorismate mutase. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.882 |
SHI72648.1 | trpF | SAMN02745194_00951 | SAMN02745194_01443 | Chorismate mutase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.692 |
SHJ39369.1 | SHI72648.1 | SAMN02745194_02449 | SAMN02745194_00951 | 2,3-dihydroxybenzoate-AMP ligase. | Chorismate mutase. | 0.708 |
SHJ39369.1 | SHJ39401.1 | SAMN02745194_02449 | SAMN02745194_02450 | 2,3-dihydroxybenzoate-AMP ligase. | Aryl carrier domain-containing protein. | 0.999 |
SHJ39369.1 | trpE | SAMN02745194_02449 | SAMN02745194_04389 | 2,3-dihydroxybenzoate-AMP ligase. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.877 |
SHJ39401.1 | SHI72648.1 | SAMN02745194_02450 | SAMN02745194_00951 | Aryl carrier domain-containing protein. | Chorismate mutase. | 0.717 |
SHJ39401.1 | SHJ39369.1 | SAMN02745194_02450 | SAMN02745194_02449 | Aryl carrier domain-containing protein. | 2,3-dihydroxybenzoate-AMP ligase. | 0.999 |
SHJ39401.1 | trpD | SAMN02745194_02450 | SAMN02745194_04392 | Aryl carrier domain-containing protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.459 |
SHJ39401.1 | trpE | SAMN02745194_02450 | SAMN02745194_04389 | Aryl carrier domain-containing protein. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.923 |
SHK18775.1 | SHI72648.1 | SAMN02745194_04391 | SAMN02745194_00951 | Anthranilate synthase component 2. | Chorismate mutase. | 0.882 |
SHK18775.1 | aroC | SAMN02745194_04391 | SAMN02745194_04430 | Anthranilate synthase component 2. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.940 |
SHK18775.1 | trpA | SAMN02745194_04391 | SAMN02745194_01446 | Anthranilate synthase component 2. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.988 |
SHK18775.1 | trpB | SAMN02745194_04391 | SAMN02745194_01445 | Anthranilate synthase component 2. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.993 |
SHK18775.1 | trpC | SAMN02745194_04391 | SAMN02745194_04393 | Anthranilate synthase component 2. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |