| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKU10462.1 | glnE | AzCIB_0557 | AzCIB_0913 | Putative ATP-dependent helicase. | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.536 |
| AKU10483.1 | AKU14053.1 | AzCIB_0578 | AzCIB_4160 | L-glutamine synthetase. | Glutamate synthase. | 0.686 |
| AKU10483.1 | glnD | AzCIB_0578 | AzCIB_2227 | L-glutamine synthetase. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.604 |
| AKU10483.1 | glnE | AzCIB_0578 | AzCIB_0913 | L-glutamine synthetase. | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.786 |
| AKU10483.1 | nadE | AzCIB_0578 | AzCIB_3083 | L-glutamine synthetase. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.563 |
| AKU10816.1 | AKU10817.1 | AzCIB_0911 | AzCIB_0912 | Phosphohistidine phosphatase SixA. | Hypothetical protein. | 0.696 |
| AKU10816.1 | glnE | AzCIB_0911 | AzCIB_0913 | Phosphohistidine phosphatase SixA. | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.521 |
| AKU10817.1 | AKU10816.1 | AzCIB_0912 | AzCIB_0911 | Hypothetical protein. | Phosphohistidine phosphatase SixA. | 0.696 |
| AKU10817.1 | glnE | AzCIB_0912 | AzCIB_0913 | Hypothetical protein. | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.565 |
| AKU10819.1 | AKU10820.1 | AzCIB_0914 | AzCIB_0915 | Hypothetical protein. | Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase. | 0.854 |
| AKU10819.1 | AKU10821.1 | AzCIB_0914 | AzCIB_0916 | Hypothetical protein. | Zn-dependent peptidase, potential modulator of DNA gyrase. | 0.728 |
| AKU10819.1 | glnE | AzCIB_0914 | AzCIB_0913 | Hypothetical protein. | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.564 |
| AKU10820.1 | AKU10819.1 | AzCIB_0915 | AzCIB_0914 | Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase. | Hypothetical protein. | 0.854 |
| AKU10820.1 | AKU10821.1 | AzCIB_0915 | AzCIB_0916 | Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase. | Zn-dependent peptidase, potential modulator of DNA gyrase. | 0.678 |
| AKU10820.1 | AKU14053.1 | AzCIB_0915 | AzCIB_4160 | Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase. | Glutamate synthase. | 0.557 |
| AKU10820.1 | glnE | AzCIB_0915 | AzCIB_0913 | Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase. | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.650 |
| AKU10821.1 | AKU10819.1 | AzCIB_0916 | AzCIB_0914 | Zn-dependent peptidase, potential modulator of DNA gyrase. | Hypothetical protein. | 0.728 |
| AKU10821.1 | AKU10820.1 | AzCIB_0916 | AzCIB_0915 | Zn-dependent peptidase, potential modulator of DNA gyrase. | Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase. | 0.678 |
| AKU10821.1 | glnE | AzCIB_0916 | AzCIB_0913 | Zn-dependent peptidase, potential modulator of DNA gyrase. | Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] | 0.558 |
| AKU14053.1 | AKU10483.1 | AzCIB_4160 | AzCIB_0578 | Glutamate synthase. | L-glutamine synthetase. | 0.686 |
