AKU10821.1 protein (Azoarcus sp. CIB) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AKU10821.1

Zn-dependent peptidase, potential modulator of DNA gyrase. (481 aa)

Predicted Functional Partners:

AKU10796.1

0.905

AKU10819.1

0.728

AKU10820.1

0.678

glnE

0.558

coaE

0.517

Your Current Organism:

Azoarcus sp. CIB

NCBI taxonomy Id: 198107
Other names: A. sp. CIB

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKU10796.1	AKU10821.1	AzCIB_0891	AzCIB_0916	Zn-dependent protease, modulator of DNA gyrase.	Zn-dependent peptidase, potential modulator of DNA gyrase.	0.905
AKU10819.1	AKU10820.1	AzCIB_0914	AzCIB_0915	Hypothetical protein.	Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase.	0.854
AKU10819.1	AKU10821.1	AzCIB_0914	AzCIB_0916	Hypothetical protein.	Zn-dependent peptidase, potential modulator of DNA gyrase.	0.728
AKU10819.1	glnE	AzCIB_0914	AzCIB_0913	Hypothetical protein.	Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]	0.564
AKU10820.1	AKU10819.1	AzCIB_0915	AzCIB_0914	Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase.	Hypothetical protein.	0.854
AKU10820.1	AKU10821.1	AzCIB_0915	AzCIB_0916	Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase.	Zn-dependent peptidase, potential modulator of DNA gyrase.	0.678
AKU10820.1	glnE	AzCIB_0915	AzCIB_0913	Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase.	Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]	0.650
AKU10821.1	AKU10796.1	AzCIB_0916	AzCIB_0891	Zn-dependent peptidase, potential modulator of DNA gyrase.	Zn-dependent protease, modulator of DNA gyrase.	0.905
AKU10821.1	AKU10819.1	AzCIB_0916	AzCIB_0914	Zn-dependent peptidase, potential modulator of DNA gyrase.	Hypothetical protein.	0.728
AKU10821.1	AKU10820.1	AzCIB_0916	AzCIB_0915	Zn-dependent peptidase, potential modulator of DNA gyrase.	Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase.	0.678
AKU10821.1	coaE	AzCIB_0916	AzCIB_0570	Zn-dependent peptidase, potential modulator of DNA gyrase.	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	0.517
AKU10821.1	glnE	AzCIB_0916	AzCIB_0913	Zn-dependent peptidase, potential modulator of DNA gyrase.	Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]	0.558
coaE	AKU10821.1	AzCIB_0570	AzCIB_0916	dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.	Zn-dependent peptidase, potential modulator of DNA gyrase.	0.517
glnE	AKU10819.1	AzCIB_0913	AzCIB_0914	Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]	Hypothetical protein.	0.564
glnE	AKU10820.1	AzCIB_0913	AzCIB_0915	Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]	Nitrilase/cyanide hydratase/apolipoprotein N-acyltransferase.	0.650
glnE	AKU10821.1	AzCIB_0913	AzCIB_0916	Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]	Zn-dependent peptidase, potential modulator of DNA gyrase.	0.558