Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKU10889.1Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (935 aa)    
Predicted Functional Partners:
AKU10887.1
Dihydrolipoamide dehydrogenase.
 
 0.999
AKU10888.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
AKU11757.1
Dihydrolipoamide dehydrogenase.
 
 0.988
AKU10922.1
Pyruvate dehydrogenase E2 component.
  
 0.987
AKU13750.1
Pyruvate dehydrogenase E2 component.
  
 0.986
AKU12181.1
Dihydrolipoamide dehydrogenase.
  
 0.985
AKU12532.1
Hypothetical protein.
 
 0.973
AKU10446.1
Fused malic enzyme predicted oxidoreductase/predicted phosphotransacetylase.
  
 
 0.952
AKU13104.1
Fused malic enzyme predicted oxidoreductase/predicted phosphotransacetylase.
  
 
 0.952
AKU12780.1
Pyruvate oxidoreductase.
     
 0.936
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (28%) [HD]