Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKU10919.1acetyl-CoA synthetase. (587 aa)    
Predicted Functional Partners:
AKU10922.1
Pyruvate dehydrogenase E2 component.
 
 
 0.982
pdhA
Pyruvate dehydrogenase E1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
 0.963
AKU10921.1
Pyruvate dehydrogenase E1 component (beta subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
  
 0.963
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.950
AKU12780.1
Pyruvate oxidoreductase.
  
 
 0.937
AKU11760.1
Citrate synthase; Belongs to the citrate synthase family.
  
 0.932
AKU14038.1
Coenzyme A transferase.
  
 0.927
AKU14050.1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.926
AKU13254.1
propionate--CoA ligase.
  
  
 
0.922
AKU13892.1
acetyl-CoA synthetase.
  
  
 
0.921
Your Current Organism:
Azoarcus sp. CIB
NCBI taxonomy Id: 198107
Other names: A. sp. CIB
Server load: low (22%) [HD]